Open AccessMito-Mendelian interactions alter in vivo glucose metabolism and insulin sensitivity in healthy mice
Author(s) -
Melissa J Sammy,
Ashley W Connelly,
Jamelle Brown,
Cassie Holleman,
Kirk M. Habegger,
Scott W. Ballinger
Publication year - 2021
Publication title -
endocrinology and metabolism/american journal of physiology: endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.507
H-Index - 201
eISSN - 1522-1555
pISSN - 0193-1849
DOI - 10.1152/ajpendo.00069.2021
Subject(s) - endocrinology , medicine , insulin , biology , insulin resistance , carbohydrate metabolism , metabolism , glucose homeostasis , insulin receptor , mitochondrial dna , type 2 diabetes , homeostasis , diabetes mellitus , genetics , gene
Different mitochondrial DNAs on the same nuclear genetic background can significantly impact body composition, glucose metabolism, and insulin sensitivity in healthy mice.