Open AccessUbiquitin E3 ligase Atrogin-1 protein is regulated via the rapamycin-sensitive mTOR-S6K1 signaling pathway in C2C12 muscle cells
Author(s) -
Yusuke Nishimura,
Jitpisute Chunthorng-Orn,
Samuel O. Lord,
Ibrahim Musa,
Peter W.J. Dawson,
Lars Holm,
YuChiang Lai
Publication year - 2022
Publication title -
american journal of physiology. cell physiology
Language(s) - English
Resource type - Journals
eISSN - 1522-1563
pISSN - 0363-6143
DOI - 10.1152/ajpcell.00384.2021
Subject(s) - mtorc1 , protein kinase b , p70 s6 kinase 1 , pi3k/akt/mtor pathway , ubiquitin ligase , phosphorylation , microbiology and biotechnology , signal transduction , chemistry , c2c12 , protein degradation , myogenesis , biology , ubiquitin , myocyte , biochemistry , gene