Nicotinamide N-methyltransferase upregulation via the mTORC1-ATF4 pathway activation contributes to palmitate-induced lipotoxicity in hepatocytes | Zendy

Alexandra Griffiths | Zendy; Jun Wang | Zendy; Qing Song | Zendy; Iredia D. Iyamu | Zendy; Lifeng Liu | Zendy; Jooman Park | Zendy; Yuwei Jiang | Zendy; Rong Huang | Zendy; Zhenyuan Song | Zendy

Open Access

Nicotinamide N-methyltransferase upregulation via the mTORC1-ATF4 pathway activation contributes to palmitate-induced lipotoxicity in hepatocytes

Author(s) -

Alexandra Griffiths,

Jun Wang,

Qing Song,

Iredia D. Iyamu,

Lifeng Liu,

Jooman Park,

Yuwei Jiang,

Rong Huang,

Zhenyuan Song

Publication year - 2021

Publication title -

ajp cell physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.432

H-Index - 181

eISSN - 1522-1563

pISSN - 0363-6143

DOI - 10.1152/ajpcell.00195.2021

Subject(s) - lipotoxicity , atf4 , mtorc1 , downregulation and upregulation , unfolded protein response , microbiology and biotechnology , sphingosine kinase , hepatocyte , biology , chemistry , signal transduction , endocrinology , biochemistry , sphingosine , pi3k/akt/mtor pathway , endoplasmic reticulum , insulin resistance , sphingosine 1 phosphate , insulin , receptor , gene , in vitro

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