Open Access2021 Joseph W. Richards Fellowship – Summary Report: Toward On-Chip Electronic Monitoring of Bacterial Conjugation
Author(s) -
Derrick Butler
Publication year - 2021
Publication title -
the electrochemical society interface
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.568
H-Index - 46
eISSN - 1944-8783
pISSN - 1064-8208
DOI - 10.1149/2.f05214if
Subject(s) - nanotechnology , chip , throughput , virulence , population , materials science , chemistry , computer science , telecommunications , wireless , biochemistry , medicine , environmental health , gene
Intercellular conjugation is a primary communication method by which bacteria transfer genetic material from one cell to another. Because conjugation mediates the transfer of genetic material, it enables the spread of antibiotic resistance and other virulence factors within a population. Current techniques for its study have low throughput and require extensive sample preparation, making real-time monitoring of conjugation dynamics challenging.To address these shortcomings, we are exploring two-dimensional (2D) materials as a strain-sensitive platform for on-chip, electronic monitoring of conjugation events.