Open AccessPulsed High-Intensity Focused Ultrasound Enhances Apoptosis and Growth Inhibition of Squamous Cell Carcinoma Xenografts with Proteasome Inhibitor Bortezomib
Author(s) -
Jason A. Poff,
Clint Allen,
Bryan Traughber,
Paul Nghiem,
Jianwu Xie,
Zhong Chen,
Bradford J. Wood,
Carter Van Waes,
King C. Li,
Victor Frenkel
Publication year - 2008
Publication title -
radiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.118
H-Index - 295
eISSN - 1527-1315
pISSN - 0033-8419
DOI - 10.1148/radiol.2482071674
Subject(s) - bortezomib , medicine , proteasome inhibitor , apoptosis , cd31 , urology , pathology , immunohistochemistry , multiple myeloma , biochemistry , chemistry
To investigate whether combining pulsed high-intensity focused ultrasound (HIFU) with the chemotherapeutic drug bortezomib could improve antitumor activity against murine squamous cell carcinoma (SCC) tumors.