Open AccessAssociation of Parvovirus B19 with Rheumatic Diseases
Author(s) -
Chi Kit Au,
Tin Lok Lai,
Cheuk Wan Yim
Publication year - 2021
Publication title -
journal of clinical rheumatology and immunology
Language(s) - English
Resource type - Journals
eISSN - 2661-3425
pISSN - 2661-3417
DOI - 10.1142/s2661341721300044
Subject(s) - rheumatoid arthritis , immunology , parvovirus , medicine , pathogenesis , vasculitis , immune system , arthritis , dermatology , disease , virus , pathology
Human parvovirus B19 infections are well reported to be associated with different autoimmune disorders. They can either mimic or trigger autoimmune diseases, such as systemic lupus erythematous (SLE), rheumatoid arthritis (RA), and vasculitis. A lack of awareness about this infection can result in delays in diagnosis and poor care. In this review, the basic biology and clinical aspects of the parvovirus, human immune response, and the pathogenesis in the rheumatic diseases are discussed.