Open AccessTherapeutic Plasma Exchange in Patients with Systemic Lupus Erythematosus
Author(s) -
Cheuk Man Ho,
Chi Chiu Mok
Publication year - 2020
Publication title -
journal of clinical rheumatology and immunology
Language(s) - English
Resource type - Journals
eISSN - 2661-3425
pISSN - 2661-3417
DOI - 10.1142/s2661341720300062
Subject(s) - plasmapheresis , therapeutic plasma exchange , medicine , refractory (planetary science) , therapeutic approach , therapeutic effect , systemic lupus erythematosus , immunology , disease , lupus erythematosus , autoimmune disease , intensive care medicine , physics , antibody , astrobiology
Systemic lupus erythematosus (SLE) is an autoimmune disease with involvement of multiple systems. Despite the therapeutic advances in the past few decades, refractory SLE causing organ damage and life-threatening complications still poses a therapeutic challenge. Therapeutic plasma exchange is considered as one of the rescue therapies used in refractory SLE. However, the level of evidence supporting its use is low. This article reviews the current evidence of the application of plasmapheresis in the treatment of SLE.