Open AccessFrom Laboratory to Patient: The Evolving Path to Become a Medicine
Author(s) -
Ana HidalgoSimon
Publication year - 2019
Publication title -
molecular frontiers journal
Language(s) - English
Resource type - Journals
eISSN - 2529-7333
pISSN - 2529-7325
DOI - 10.1142/s2529732519400121
Subject(s) - authorization , permission , process (computing) , product (mathematics) , risk analysis (engineering) , computer science , path (computing) , data science , medicine , engineering ethics , computer security , engineering , political science , law , geometry , mathematics , operating system , programming language
Gene editing and other laboratory developments promise to revolutionize treatment of many diseases that currently have no cure. The process to become a medicine is long and complex and requires many years. Regulation of medicines (permission to market a product and monitoring of its performance) is evolving to adapt to emerging new approaches in development. Current issues and new ideas needed to navigate the difficult waters from laboratory to patient are discussed here: novel approaches for narrow evidence base, earlier discussions of evidence with regulators, earlier planning for post-authorization requirements and better patient access.