Open AccessElectrospun antibacterial nanofibers for wound dressings and tissue medicinal fields: A Review
Author(s) -
Zhimei Wei,
Liqun Wang,
Shouyu Zhang,
Tonghai Chen,
Jie Yang,
Shengru Long,
Xiaojun Wang
Publication year - 2020
Publication title -
journal of innovative optical health sciences/journal of innovation in optical health science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.421
H-Index - 24
eISSN - 1793-5458
pISSN - 1793-7205
DOI - 10.1142/s1793545820300128
Subject(s) - electrospinning , nanofiber , wound dressing , nanotechnology , materials science , expansive , wound healing , antibacterial peptide , antibacterial activity , biomedical engineering , medicine , surgery , composite material , polymer , bacteria , biology , genetics , compressive strength
Bacterial infections are a major cause of chronic infections. Thus, antibacterial material is an urgent need in clinics. Antibacterial nanofibers, with expansive surface area, enable efficient incorporation of antibacterial agents. Meanwhile, structure similar to the extracellular matrix can accelerate cell growth. Electrospinning, the most widely used technique to fabricate nanofiber, is often used in many biomedical applications including drug delivery, regenerative medicine, wound healing and so on. Thus, this review provides an overview of all recently published studies on the development of electrospun antibacterial nanofibers in wound dressings and tissue medicinal fields. This reviewer begins with a brief introduction of electrospinning process and then discusses electrospun fibers by incorporating various types of antimicrobial agents used as in wound dressings and tissue. Finally, we finish with conclusions and further perspectives on electrospun antibacterial nanofibers as 2D biomedicine materials.