Open AccessAUTOMATED ASSESSMENT OF EPIDERMAL THICKNESS AND VASCULAR DENSITY OF PORT WINE STAINS OCT IMAGE
Author(s) -
Chengming Wang,
Tiancheng Huo,
Jingyi Zheng,
Ning Zhang,
Tianyuan Chen,
Wenchao Liao,
Ying Wang,
Ying Gu,
Ping Xue
Publication year - 2014
Publication title -
journal of innovative optical health sciences/journal of innovation in optical health science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.421
H-Index - 24
eISSN - 1793-5458
pISSN - 1793-7205
DOI - 10.1142/s1793545813500521
Subject(s) - port wine , optical coherence tomography , biomedical engineering , intensity (physics) , dermis , medicine , computer science , materials science , dermatology , radiology , pathology , optics , surgery , physics
Optical coherence tomography (OCT) enables in vivo imaging of port wine stains (PWS) lesions. The knowledge of vascular structure and epidermal thickness (ET) of PWS may aid the objective diagnosis and optimal treatment. To obtain the structural parameters more rapidly and avoid user intervention, an automated algorithm of energy map is introduced based on intensity and edge information to extract the skin surface using dynamic programming method. Subsequently, an averaged A-scan analysis is performed to obtain the mean ET and the relative intensity of dermis indicating the corresponding vascular density. This approach is currently successfully applied in clinical diagnosis and shows promising guidance and assessment of PDT treatment