Open AccessEffect of a single dose of subcutaneous meloxicam before knife castration alone or combined with hot-iron branding on scrotal healing, inflammatory response, and behaviour in 2-mo-old beef calves over 42 d post procedure
Author(s) -
Sonia Martí,
Daniela M Meléndez,
E. A. Pajor,
Diego Moya,
D. Gellatly,
E. D. Janzen,
K. S. Schwartzkopf-Genswein
Publication year - 2019
Publication title -
canadian journal of animal science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.377
H-Index - 64
eISSN - 1918-1825
pISSN - 0008-3984
DOI - 10.1139/cjas-2018-0016
Subject(s) - castration , meloxicam , medicine , haptoglobin , crossbreed , orchiectomy , subcutaneous injection , inflammation , scrotum , zoology , surgery , biology , hormone
The objective of this study was to evaluate the effect of a single subcutaneous injection of meloxicam on scrotal healing, inflammatory response, and behaviour in castrated or castrated and branded beef calves for 42 d post procedure. Seventy-two 2-mo-old Angus crossbred bull calves were used to assess the effects of procedure (Trt): (1) sham control, (2) knife castration, and (3) knife castration and hot-iron branding; and pain mitigation (Med): (1) nonmedicated and (2) medicated with meloxicam according to a 3 × 2 factorial design. Body weight, scrotal circumference (SC), and healing scores were collected weekly until day 42. Blood samples were collected weekly until day 42 to assess haptoglobin, serum amyloid-A, and complete blood cell count. Hair was collected on day −1 and day 42 to assess cortisol concentrations. Lying and standing behaviour were recorded for 42 d, whereas pain-related behaviours were recorded on days 7, 15, 22, 29, and 34 post procedure. The inflammatory response (SC) and duration of standing was greater (P < 0.05) in calves castrated and branded than those only castrated. However, meloxicam did not reduce inflammation or improve wound healing in either castrated or castrated and branded calves.