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Comparison of a chlorhexidine and a benzoyl peroxide shampoo as sole treatment in canine superficial pyoderma
Author(s) -
Loeffler A.,
Cobb M. A.,
Bond R.
Publication year - 2011
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.d4400
Subject(s) - pyoderma , shampoo , benzoyl peroxide , chlorhexidine , dermatology , medicine , chemistry , dentistry , pathology , organic chemistry , polymerization , polymer
The clinical and antibacterial efficacy of two shampoos used as a sole antibacterial treatment in dogs with superficial pyoderma were investigated and compared. In a randomised, partially blinded study, a 3 per cent chlorhexidine gluconate shampoo (Chlorhex 3; Leo Animal Health) was compared against a 2.5 per cent benzoyl peroxide shampoo (Paxcutol; Virbac) in 22 dogs with superficial pyoderma. Dogs were washed two to three times weekly with a 10‐minute contact time over 21 days. Clinical scores and bacterial counts were assessed on days 1, 8 and 22 and compared within and between treatment groups; overall response was assessed at the end of the study. Twenty dogs completed the study; 15 (68.2 per cent) showed an overall clinical improvement and the clinical signs resolved in three chlorhexidine‐treated dogs. In the chlorhexidine‐treated group, scores for papules/pustules (P<0.001), investigator‐assessed pruritus (P=0.003), total bacterial counts (P=0.003) and counts for coagulase‐positive staphylococci (P=0.003) were reduced after three weeks. Scores and bacterial counts did not vary significantly in the benzoyl peroxide‐treated group.

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