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Effect of tulathromycin on the carrier status of Actinobacillus pleuropneumoniae serotype 2 in the tonsils of pigs
Author(s) -
Angen Ø.,
Andreasen M.,
Nielsen E. O.,
Stockmarr A.,
Bækbo P.
Publication year - 2008
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.163.15.445
Subject(s) - actinobacillus pleuropneumoniae , serotype , herd , veterinary medicine , tonsil , biology , actinobacillus , zoology , medicine , microbiology and biotechnology , immunology , bacteria , genetics
The effect of a single or double dose of tulathromycin was evaluated in pigs carrying Actinobacillus pleuropneumoniae serotype 2 in their tonsils. Twenty‐nine pigs from a reinfected specific pathogen‐free‐herd were selected from animals testing positive in an A pleuropneumoniae serotype 2‐specific pcr test on tonsil scrapings and they were divided into three groups. The pigs in group 1 were treated subcutaneously with 2·5 mg/kg tulathromycin on day 0, the pigs in group 2 were treated with 2·5 mg/kg tulathromycin on days 0 and 4, and the pigs in group 3 were left untreated as controls. The pigs were tested by pcr on tonsil scrapings on days 0, 4, 11 and 33, and on day 33 all the animals were euthanased. There were no significant differences between the numbers of pcr ‐positive animals in the three groups on any of the sampling dates.