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Ability of antibodies to two new caliciviral vaccine strains to neutralise feline calicivirus isolates from the uk
Author(s) -
Addie D.,
Poulet H.,
Golder M. C.,
McDonald M.,
Brunet S.,
Thibault JC.,
Hosie M. J.
Publication year - 2008
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.163.12.355
Subject(s) - feline calicivirus , antiserum , virology , calicivirus , biology , caliciviridae , microbiology and biotechnology , antibody , cats , virus , medicine , viral disease , immunology
This study examined a panel of 110 uk field isolates of feline calicivirus ( fcv ) for susceptibility to cross‐neutralisation by a panel of eight antisera raised in cats infected with fcv strains F9, 255, fcvg1 and fcv431 . The pairs of antisera raised against F9 or 255, neutralised 20 and 21 per cent or 37 and 56 per cent of field strains of virus respectively. In contrast, the pairs of antisera raised against the newer vaccine strains fcvg1 or fcv431 neutralised 29 and 70 per cent or 67 and 87 per cent of field strains respectively. Antisera raised against the two newer strains, namely fcvg1 and fcv431 , neutralised a greater proportion of field strains of calicivirus than antisera raised against the older fcv vaccine strains F9 and 255.