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Effects of sedation with acepromazine on echocardiographic measurements in eight healthy thoroughbred horses
Author(s) -
MenziesGow N. J.
Publication year - 2008
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.163.1.21
Subject(s) - acepromazine , sedation , medicine , diastole , systole , cardiology , detomidine , interventricular septum , aorta , horse , pulmonary artery , cardiac cycle , anesthesia , heart rate , blood pressure , biology , paleontology , ventricle
Eight normal thoroughbred horses were examined by echocardiography before and 10 minutes after they had been sedated by the intravenous administration of 0·03 mg/kg acepromazine. There were significant (P<0·025) increases in the diameters of the pulmonary artery and the aorta, measured at end‐systole, and in the thickness of the interventricular septum, measured at end‐systole and end‐diastole. In addition, there was a significant (P<0·001) decrease in the diameter of the left atrium measured at end‐diastole. The remaining cardiac dimensions, all the indices of cardiac function, and the occurrence and severity of valvular regurgitation were not affected by sedation.