Premium
Plasma concentrations of voriconazole in falcons
Author(s) -
Schmidt V.,
Demiraj F.,
Di Somma A.,
Bailey T.,
Ungemach F. R.,
KrautwaldJunghanns ME.
Publication year - 2007
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.161.8.265
Subject(s) - plasma concentration , voriconazole , zoology , biology , medicine , pharmacology , antifungal , microbiology and biotechnology
Doses of 12·5 mg voriconazole/kg bodyweight administered every 12 hours by crop gavage to six falcons for 14 days provided peak plasma concentrations of more than 1 μg/ml, but the trough concentrations were lower and sometimes undetectable. Administering the same doses incorporated into meat that was fed to one falcon for seven days and to three falcons for up to 91 days provided similar plasma concentrations.