Premium
Acquired idiopathic laryngeal paralysis as a prominent feature of generalised neuromuscular disease in 39 dogs
Author(s) -
Jeffery N. D.,
Talbot C. E.,
Smith P. M.,
Bacon N. J.
Publication year - 2006
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.158.1.17
Subject(s) - medicine , myasthenia gravis , paralysis , weakness , neuromuscular disease , muscle weakness , thyroid , disease , anesthesia , surgery
A retrospective evaluation of 17 dogs treated surgically for idiopathic acquired laryngeal paralysis demonstrated a marked variability in outcome, with many dogs continuing to exhibit weakness and exercise tolerance. In a subsequent prospective study, 22 consecutive affected dogs were tested for neurological deficits by neurological examination, electrodiagnostic evaluation, and blood analysis to measure thyroxine and thyroid‐stimulating hormone and to detect any evidence of myasthenia gravis. Clinical neurological deficits and/or electrodiagnostic abnormalities were found in each case. There was limited evidence that specific neurological deficits were associated with a poor prognosis for full recovery of exercise tolerance. None of the dogs was positive for anti‐acetylcholine receptor antibodies, and only three showed evidence of thyroid dysfunction.