Premium
Effects of surgery on the acute phase response in clinically normal and diseased horses
Author(s) -
Pollock P. J.,
Prendergast M.,
Schumacher J.,
Bellenger C. R.
Publication year - 2005
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.156.17.538
Subject(s) - elective surgery , haptoglobin , medicine , fibrinogen , acute phase protein , serum amyloid a , surgery , anesthesia , gastroenterology , inflammation
The serum concentrations of serum amyloid A, haptoglobin and fibrinogen were measured in a group of horses before and at intervals after elective and non‐elective surgery, and in a control group of normal horses. There was a significant, rapid and repeatable increase in the concentration of serum amyloid A in response to both elective and non‐elective surgery. In the control horses its serum concentration was within the normal range, from 0 to 0·2 µg/ml. Twenty‐four hours after elective surgery its mean peak concentration was 16·4 µg/ml, and after non‐elective surgery it was 27·3 µg/ml. In contrast, the serum concentrations of haptoglobin and fibrinogen increased more slowly after surgery and had not decreased by 72 hours after surgery.