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Review of the properties and mechanisms of action of cyclosporine with an emphasis on dermatological therapy in dogs, cats and people
Author(s) -
Robson D.
Publication year - 2003
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.152.25.768
Subject(s) - cats , action (physics) , medicine , emphasis (telecommunications) , pharmacology , computer science , physics , quantum mechanics , telecommunications
Cyclosporine is being increasingly used in veterinary medicine. It is a potent suppressor of T cell induction and proliferation, and has a wide variety of anti‐inflammatory and antiproliferative effects, downregulating efects on antigen presentation, and variable effects on parasites. This paper reviews its properties and mechanisms of action with particular reference to its use in the treatment of dermatological conditions in dogs, cats and people.