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Isoflurane to prolong medetomidine/ketamine anaesthesia in six adult female chimpanzees ( Pan troglodytes )
Author(s) -
Adams W. A.,
Robinson K. J.,
Jones R. S.,
Sanderson S.
Publication year - 2003
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.152.1.18
Subject(s) - medetomidine , atipamezole , isoflurane , ketamine , anesthesia , medicine , general anaesthesia , xylazine , heart rate , blood pressure
Six adult female chimpanzees ( Pan troglodytes ) were anaesthetised for the placement of intrauterine contraceptive devices, microchips for identification, routine blood sampling, and physical measurements. Anaesthesia was induced with medetomidine in combination with ketamine administered by intramuscular injection with a projectile syringe. Induction was smooth and rapid, but five of the animals were insufficiently relaxed for orotracheal intubation. The plane of anaesthesia was deepened by administering isoflurane delivered in oxygen and nitrous oxide, and general anaesthesia was maintained for up to 74 minutes. The action of medetomidine was reversed at the end of each procedure with atipamezole, and the animals recovered smoothly and uneventfully.