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Biochemical changes induced by hypomagnesaemia in lactating cows and ewes
Author(s) -
McCoy M. A.,
Young P. B.,
Edgar H. W. J.,
McCarville E. M.,
Davison G.,
Kennedy D. G.,
Fitzpatrick D. A.
Publication year - 2002
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.150.6.176
Subject(s) - medicine , endocrinology , lipid peroxidation , biology , zoology , platelet , chemistry , oxidative stress
Severe hypomagnesaemia was induced in lactating cows and lactating sheep by feeding them magnesium‐deficient diets for 17 and 14 days, respectively. Hypomagnesaemia in cows was associated with abnormally high rates of change in the numbers of leucocytes, neutrophils, monocytes and platelets. There were increases in the concentration of iron in the liver of the hypomagnesaemic ewes and in the heart of the hypomagnesaemic cows, which were not associated with a haemolytic process. The percentage of some of the peroxidisable fatty acids was lower in the heart tissue of hypomagnesaemic cows, but the reduction was not associated with significant lipid peroxidation.