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Evaluation and optimisation of a targetcontrolled infusion system for administering propofol to dogs as part of a total intravenous anaesthetic technique during dental surgery
Author(s) -
Beths T.,
Reid J.,
Monteiro A. M.,
Nolan A. M.,
Glen J. B.
Publication year - 2001
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.148.7.198
Subject(s) - propofol , medicine , anesthesia , dental surgery , target controlled infusion , dentistry , remifentanil
The performance of a modified target‐controlled infusion system was investigated in 16 dogs undergoing routine dental work, by comparing the predicted concentrations of propofol in venous blood samples with direct measurements; the optimum targets for the induction and maintenance of anaesthesia were also identified. The performance of a target‐controlled infusion system is considered clinically acceptable when the median prediction error, a measure of bias, is not greater than ±10 to 20 per cent, and the median absolute performance error, a measure of the accuracy, is not greater than 20 to 30 per cent. The results fell within these limits indicating that the system performed adequately. The optimal induction target was 3 μg/ml, and anaesthesia of adequate depth and satisfactory quality was achieved with maintenance targets of between 2.5 and 4.7 μg/ml propofol. The system was easy to use and the quality of anaesthesia was adequate for dental work.