Premium
Efficacy of an inactivated oil emulsion vaccine against hydropericardium syndrome in broilers
Author(s) -
Roy P.,
Koteeswaran A.,
Manickam R.
Publication year - 1999
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.145.16.458
Subject(s) - seroconversion , ouchterlony double immunodiffusion , inactivated vaccine , emulsion , vaccination , immunodiffusion , agar , medicine , radial immunodiffusion , veterinary medicine , virology , microbiology and biotechnology , biology , immunology , antibody , virus , antiserum , biochemistry , genetics , bacteria
Two inactivated vaccines were prepared against hydropericardium syndrome. The vaccine prepared from liver homogenate extracted with chloroform, inactivated with formalin and adjuvanted with liquid paraffin was highly effective against challenge in chickens aged three, five and seven weeks. Seroconversion following vaccination and challenge was assessed by the agar gel immunodiffusion test. The inactivated oil emulsion vaccine was highly effective against the syndrome in both experimental trials and field trials.