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Analysis of scintigraphical lung images before and after treatment of horses suffering from chronic pulmonary disease
Author(s) -
Votion D.,
Ghafir Y.,
Vandenput S.,
Duvivier D. H.,
Art T.,
Lekeux P.
Publication year - 1999
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.144.9.232
Subject(s) - medicine , pulmonary function testing , perfusion , lung , horse , inhalation , pulmonary disease , cardiology , anesthesia , biology , paleontology
Scintigraphical analysis of the ratio of inhalation (i) to perfusion (Q) was designed to determine whether chronic pulmonary disease in horses induced mismatches in i/Q and to assess whether medical treatment would restore an I/Q distribution pattern identical to that of control horses. In addition, the results of the I/Q analysis were correlated with the alveolar‐arterial PO 2 difference (AaDO 2 ). The I/Q matching found in a group of control horses was compared with the I/Q analysis of a group of diseased horses before and after their clinical signs had been treated. The analysis indicated that there was mismatching between I and Q before they were treated. The treatment improved the diseased horses, pulmonary function but there was still heterogeneity in the I/Q distribution after they had been treated. The i/Q analysis parameters were well correlated with the ratio of ventilation (V A ) and pulmonary blood flow (Q), evaluated by the determination of AaDO 2 .