Premium
Level and duration of serum antibodies in cattle infected experimentally and naturally with bovine virus diarrhoea virus
Author(s) -
Fredriksen B.,
Sandvik T.,
Løken T.,
Ødegaard S. A.
Publication year - 1999
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.144.5.111
Subject(s) - virus , virology , antibody , inoculation , biology , nasal administration , antibody response , blood serum , immunology , endocrinology
Neutralising serum antibodies against bovine virus diarrhoea virus (BVDV) were monitored for three years in 35 cattle that were infected with the virus as calves; 24 of the calves were inoculated intramuscularly or intranasally, and 11 contracted the infection naturally. All the experimentally infected calves seroconverted within 14 to 28 days after inoculation, and all the animals still had high serum levels of antibodies to BvDv three years after infection. Determinations of antibody levels in milk and blood samples excluded the possibility that the calves had been reinfected with BvDv during the study.