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Unusual case of metabolic bone disease in a common marmoset ( Callithrix jacchus )
Author(s) -
Hatt JM.,
Sainsbury A. W.
Publication year - 1998
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.143.3.78
Subject(s) - callithrix , osteomalacia , marmoset , metabolic bone disease , rickets , medicine , nephrocalcinosis , endocrinology , calcification , hyperparathyroidism , osteoporosis , pathology , vitamin d and neurology , biology , kidney , paleontology
Metabolic bone disease was diagnosed in an 11‐month‐old female common marmoset ( Callithrix jacchus ). It was depressed, reluctant to move, and was cachectic and small for its age. Laboratory findings included anaemia, azotaemia and an inverse calcium to phosphorus ratio. The radiological findings showed simultaneous signs of osteomalacia and softtissue calcification. There was decreased bone density with lytic areas in the pelvis and femur, and severe bilateral nephrocalcinosis. Postmortem examination revealed marked focal dystrophic calcification of the epi‐ and myocardium. Calcium and vitamin D3 deficiency (nutritional secondary hyperparathyroidism) was the most likely cause of the osteomalacia.