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Xanthine urolithiasis in a dachshund
Author(s) -
Flegel T.,
Freistadt R.,
Haider W.
Publication year - 1998
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.143.15.420
Subject(s) - xanthine , uric acid , xanthine oxidase , catabolism , urine , chemistry , transformation (genetics) , medicine , xanthine dehydrogenase , endocrinology , enzyme , biochemistry , gene
Calculi were located in the kidneys, the ureters and the bladder of a two‐year‐old male dachshund. The yellow‐greenish calculi developed as a result of impaired transformation of xanthine to uric acid resulting in an increased concentration of xanthine in the urine. The cause of the impaired catabolism of xanthine was probably a disorder of the xanthine oxidase enzyme, which catalyses the transformation of xanthine to uric acid.