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Pergolide treatment for Cushing's syndrome in a horse
Author(s) -
Muñoz M. C.,
Doreste F.,
Ferrer O.,
González J.,
Montoya J. A.
Publication year - 1996
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.139.2.41
Subject(s) - pergolide , polyuria , medicine , neutrophilia , horse , dexamethasone , endocrinology , hirsutism , physiology , hormone , prolactin , biology , insulin , diabetes mellitus , paleontology , insulin resistance , polycystic ovary , bromocriptine
A 16‐year‐old, male, Hanoverian horse had a three‐month history of weight loss, hirsutism and polyuria/polydypsia. Examinations revealed neutrophilia, lymphopenia, hyper glycaemia and abnormalities in hepatic function. A tentative diagnosis of hyperadrenocorticism was made. The results of thyroid‐releasing hormone and combined dexamethasone suppression and ACTH stimulation tests suggested the presence of a pituitary adenoma. The horse was treated with pergolide and benefical clinical and biochemical responses were observed within one to six months.