Premium
Papillary ductal adenocarcinoma in the mammary glands of two horses
Author(s) -
Reppas G. P.,
McClintock S. A.,
Canfield P. J.,
Watson G. F.
Publication year - 1996
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.138.21.518
Subject(s) - histopathology , stroma , mammary gland , pathology , immunohistochemistry , papillary adenocarcinoma , medicine , mastitis , adenocarcinoma , cytology , infiltration (hvac) , hormone , progesterone receptor , ductal carcinoma , cancer , breast cancer , estrogen receptor , physics , thermodynamics
Mammary gland neoplasms in horses are uncommon and may initially be confused with mastitis. Masses from the mammary glands of two horses with chronic discharges were examined by cytology and histopathology. Both masses were diagnosed as papillary ductal adenocarcinomas with extensive intraductal and intralobular involvement and only focal infiltration of the adjacent stroma. Complementary immunohistochemical studies were made of both fresh and formalin‐fixed tumour tissue, and attempts were made to assess the steroid receptor status of fresh tissue biochemically to assess the possibility of hormonal treatment as an adjunct to surgery. The results of these tests for oestrogen and progesterone receptors were negative.