Premium
Serological survey for orthopoxvirus infection of wild mammals in areas where a recombinant rabies virus is used to vaccinate foxes
Author(s) -
Boulanger D.,
Crouch A.,
Brochier B.,
Bennett M.,
Clément J.,
Gaskell R. M.,
Baxby D.,
Pastoret P.P.
Publication year - 1996
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.138.11.247
Subject(s) - cowpox virus , orthopoxvirus , rabies , virology , biology , serology , cowpox , rabies virus , vaccinia , poxviridae , vaccination , virus , antibody , recombinant dna , immunology , biochemistry , gene
Several fox vaccination campaigns against rabies have been undertaken in Belgium by using a vaccinia‐rabies recombinant virus distributed in baits in the field. However, foxes and other wild animals that may ingest the baits could be infected at the same time by another orthopoxvirus, such as cowpox virus, which circulates in wildlife. Recombination between the two viruses could therefore occur. A serological survey for antibodies to orthopoxvirus, and particularly to cowpox virus, was undertaken in foxes and in several other wild species. Antibodies were detected only in two rodent species, in 16 of 25 bank voles (64 per cent) and in two of 29 woodmice (7 per cent). The risk of virus recombination in wildlife can therefore be considered to be extremely low.