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Influence of ageing on quantitative contrast‐enhanced ultrasound of the kidneys in healthy cats
Author(s) -
Stock Emmelie,
Paepe Dominique,
Daminet Sylvie,
Duchateau Luc,
Saunders Jimmy H,
Vanderperren Katrien
Publication year - 2018
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.104490
Subject(s) - cats , urine specific gravity , medicine , creatinine , blood pressure , ageing , urology , perfusion , renal function , urinary system , ultrasound , urine , kidney , physiology , urine osmolality , endocrinology , radiology
The degenerative effects of ageing on the kidneys have been extensively studied in humans. However, only recently interest has been focused on renal ageing in veterinary medicine. Contrast‐enhanced ultrasound allows non‐invasive evaluation of renal perfusion in conscious cats. Renal perfusion parameters were obtained in 43 healthy cats aged 1–16 years old, and the cats were divided in four age categories: 1–3 years, 3–6 years, 6–10 years and over 10 years. Routine renal parameters as serum creatinine, serum urea, urine‐specific gravity, urinary protein:creatinine ratio and systolic blood pressure were also measured. No significant differences in any of the perfusion parameters were observed among the different age categories. A trend towards a lower peak enhancement and wash‐in area under the curve with increasing age, suggestive for a lower blood volume, was detected when comparing the cats over 10 years old with the cats of 1–3 years old. Additionally, no significant age‐effect was observed for the serum and urine parameters, whereas a higher blood pressure was observed in healthy cats over 10 years old.