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Anti‐Müllerian hormone: a potential biomarker for differential diagnosis of cryptorchidism in dogs
Author(s) -
Gharagozlou F.,
Youssefi R.,
Akbarinejad V.,
Mohammadkhani N. I.,
Shahpoorzadeh T.
Publication year - 2014
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.102611
Subject(s) - theriogenology , medicine , veterinary medicine , reproductive medicine , club , family medicine , biology , reproductive biology , genetics , embryo , pregnancy , anatomy , embryogenesis , microbiology and biotechnology
Cryptorchidism, in which the testes fail to descend into the scrotum by six months of age, is a developmental disorder in male dogs (Johnston and others 2001). Cryptorchidism predisposes the animal to testicular neoplasia, therefore the retained testes should be surgically removed for the health of the animal (Johnston and others 2001). Hence, when deciding whether to perform surgery, it is diagnostically essential that cryptorchidism be differentiated from other conditions in which the testes are not present in the scrotum, including anorchidism or cases that have been castrated (England and others 1989; Johnston and others 2001).Anti-Mullerian hormone (AMH) is produced by Sertoli cells in different species of mammals, including dogs, and plays a crucial role in sexual differentiation; that is, AMH induces the regression of the paramesonephric ducts during the early embryonic development in …