z-logo
Premium
Acute‐phase protein concentration and metabolic status affect the outcome of treatment in cows with clinical and subclinical endometritis
Author(s) -
Heidarpour M.,
Mohri M.,
FallahRad A. H,
Shahreza F. Dehghan,
Mohammadi M.
Publication year - 2012
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.100947
Subject(s) - endometritis , haptoglobin , acute phase protein , subclinical infection , medicine , endocrinology , biology , pregnancy , inflammation , genetics
The aim of this study was to investigate the role of acute‐phase protein concentration and metabolic status in the establishment and resistance of clinical endometritis (CE) and subclinical endometritis (SE) in dairy cows. We also characterised the treatment‐related changes in the concentration of acute‐phase proteins and metabolic variables in dairy cows affected by CE and SE. Cows of the SE and CE groups presented a significantly higher β‐hydroxybutyrate (BHB), haptoglobin and total sialic acid (TSA) concentrations compared with a healthy group of animals. A significantly lower serum calcium concentration, and a significantly higher serum aspartate aminotransferase activity in the CE group, were observed when compared with SE and healthy groups. The comparison of parameters before treatment indicated that cows suffering from CE or SE with lower concentrations of hepatic and inflammatory markers showed a better response to further treatment, and endometritis was not detected in the second examination. Moreover, decreased concentrations of BHB, acute‐phase proteins and hepatic markers were observed after successful treatment for endometritis in CE and SE cows. The results obtained in this study suggest that improved liver function and a decrease in the acute‐phase protein concentration might favour the resolution of endometritis after treatment.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here