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Pituitary macroadenoma leading to hypogonadism in a dog
Author(s) -
TørnqvistJohnsen Camilla,
Woods Glynn A,
Tan Yi Lin,
Schwarz Tobias,
Blackwood Laura,
Mellanby Richard J,
Salavati Silke
Publication year - 2020
Publication title -
veterinary record case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.165
H-Index - 4
ISSN - 2052-6121
DOI - 10.1136/vetreccr-2020-001192
Subject(s) - lethargy , medicine , asymptomatic , pituitary disease , physical examination , testosterone (patch) , endocrinology , gynecology , urology , hormone
A six‐year‐old male entire dachshund presented for investigation of decreased testicular size noted over the last six months and progressive lethargy for two months. Apart from small symmetrical testicles and a small prostate gland, physical examination revealed no abnormalities. Neurological examination was repeatably normal. Extensive diagnostic investigations for extracranial disease with a focus on reproductive and metabolic‐endocrine disorders revealed no abnormalities. Decreased testosterone (0.2 nmol/l) with inappropriately low luteinising hormone (<0.7 iu/l) and follicle stimulating hormone (2.1 ng/ml) in comparison with six other male entire dogs was detected. Based on the exclusion of all other conditions, intracranial disease was suspected. MRI of the head revealed a 2 × 1.8 × 1.5 cm mass arising from the pituitary fossa. Radiotherapy (12 fractions of 4 Gy, three days per week for four weeks, three‐dimensional conformal plan, 6 MV) and pain relief resulted in resolution of lethargy. Twelve months after initial diagnosis, the dog was asymptomatic, while the testicles remained small.