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Use of a modified thromboelastography assay for the detection of hyperfibrinolysis in a dog infected with Angiostrongylus vasorum
Author(s) -
Cole Laura,
Barfield Dominic,
Chan Daniel L,
Cortellini Stefano
Publication year - 2018
Publication title -
veterinary record case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.165
H-Index - 4
ISSN - 2052-6121
DOI - 10.1136/vetreccr-2017-000554
Subject(s) - hyperfibrinolysis , thromboelastography , medicine , fibrinolysis , tranexamic acid , surgery , anesthesia , coagulation , blood loss
A dog presenting with scleral haemorrhage and neck pain was diagnosed with Angiostrongylus vasorum on direct faecal smear. Thromboelastography (with the addition of tissue plasminogen activator) revealed evidence of hypocoagulability and hyperfibrinolysis. The administration of fresh frozen plasma and tranexamic acid was associated with the resolution of a hypocoagulable and a hyperfibrinolytic state, as well as clinical improvement.