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Feline progressive dendritic cell histiocytosis in a domestic long hair feline
Author(s) -
Solc Meghan,
Jazic Edward,
Crandell John,
Loeffler Diana
Publication year - 2017
Publication title -
veterinary record case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.165
H-Index - 4
ISSN - 2052-6121
DOI - 10.1136/vetreccr-2017-000428
Subject(s) - medicine , histiocyte , pathology , biopsy , skin biopsy , cryptococcus , histiocytosis , cats , giant cell , dermatology , disease , biology , microbiology and biotechnology
A six‐year‐old male castrated domestic long hair feline presented for evaluation of a progressive cutaneous nodular dermatosis and an acute onset of dyspnoea. The patient had an initial skin biopsy performed with a tentative diagnosis of mycobacteriosis; however, acid‐fast stains were negative. Thoracic radiographs revealed multifocal, large pulmonary nodules. Aerobic bacterial, fungal and mycobacterial cultures, as well as Histoplasma and Cryptococcus antigen tests, were all negative. Re‐evaluation of the biopsy provided a diagnosis of feline progressive dendritic cell histiocytosis. The samples revealed a focally marked to diffuse coalescing superficial to deep perivascular and periadnexal infiltrates of numerous moderately large histiocytic cells. Unfortunately, there is no successful treatment for this disease and the patient was humanely euthanased.