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Focal cortical dysplasia resulting in seizures in an adult dog
Author(s) -
Cooper Camilla Jayne,
McConnell Fraser,
Walmsley Gemma,
Gonçalves Rita
Publication year - 2015
Publication title -
veterinary record case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.165
H-Index - 4
ISSN - 2052-6121
DOI - 10.1136/vetreccr-2015-000254
Subject(s) - cortical dysplasia , medicine , white matter , levetiracetam , grey matter , dysplasia , differential diagnosis , gyrus , epilepsy , sulcus , pathology , magnetic resonance imaging , pediatrics , radiology , anatomy , psychiatry
A two‐year‐old, neutered male, old English sheepdog was presented for further investigation of generalised tonic‐clonic seizures. MRI of the brain revealed cortical grey matter thickening, grey‐white matter blurring and malformation of the prorean and precruciate gyrus and absence of the presylvian sulcus. These findings are consistent with congenital focal cortical dysplasia; although the histopathological findings have been previously described in dogs, the MRI findings have not yet been reported in the veterinary literature. Phenobarbitone was added at the time of diagnosis with levetiracetam being added after 12 months due to worsening seizure frequency. Cortical dysplasia, although uncommon, should be considered as a differential diagnosis in an adult dog with generalised seizures.