Premium
Suspect anaphylaxis following intravenous buprenorphine administration in a dog
Author(s) -
Rossanese Matteo,
Rigotti Clara
Publication year - 2015
Publication title -
veterinary record case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.165
H-Index - 4
ISSN - 2052-6121
DOI - 10.1136/vetreccr-2015-000190
Subject(s) - medicine , anesthesia , exploratory laparotomy , nalbuphine , propofol , isoflurane , tachycardia , fentanyl , surgery , laparotomy , opioid , receptor
A seven‐month‐old French Mastiff was scheduled to undergo exploratory laparotomy for the removal of gastric foreign bodies. Buprenorphine 20 μg/kg was administered intravenously as preanaesthetic medication. Five minutes after the injection, tachypnoea, dyspnoea, cyanosis and tachycardia developed; periorbital, labial and lingual oedema were also noted. Anaesthesia was induced with 4 mg/kg of propofol, and laryngeal visualisation revealed severe laryngeal oedema. The trachea was intubated with a 6 mm endotracheal tube and anaesthesia was maintained with isoflurane in oxygen. Fluid therapy was started and glucocorticoids were administered. The exploratory laparotomy was completed and gastric foreign bodies were removed. A temporary tracheostomy was performed as no improvement of the laryngeal oedema was detected. The patient recovered uneventfully and after 48 hours the tracheostomy tube was removed successfully. The reaction may be attributed to histamine release following injection of buprenorphine.