Open AccessRespiratory exacerbations are associated with muscle loss in current and former smokers
Author(s) -
S. Mason,
Rafael Moreta-Martínez,
Wassim W. Labaki,
Matthew Strand,
David Baraghoshi,
Elizabeth A. Regan,
Jessica Bon,
R. San José Estépar,
Richard Casaburi,
Merry-Lynn McDonald,
Harry B. Rossiter,
Barry J. Make,
Mark T. Dransfield,
MeiLan K. Han,
Kendra A. Young,
Gregory L. Kinney,
John E. Hokanson,
Raúl San Jośe Estépar,
George R. Washko
Publication year - 2021
Publication title -
thorax
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.083
H-Index - 221
eISSN - 1468-3296
pISSN - 0040-6376
DOI - 10.1136/thoraxjnl-2020-215999
Subject(s) - medicine , exacerbation , copd , pectoralis muscle , wasting , body mass index , cardiology , surgery
Muscle wasting is a recognised extra-pulmonary complication in chronic obstructive pulmonary disease and has been associated with increased risk of death. Acute respiratory exacerbations are associated with reduction of muscle function, but there is a paucity of data on their long-term effect. This study explores the relationship between acute respiratory exacerbations and long-term muscle loss using serial measurements of CT derived pectoralis muscle area (PMA).