Open AccessTopographic heterogeneity of lung microbiota in end-stage idiopathic pulmonary fibrosis: the Microbiome in Lung Explants-2 (MiLEs-2) study
Author(s) -
Eleanor Valenzi,
Haopu Yang,
John Sembrat,
Liheng Yang,
Spencer Winters,
Rachel Nettles,
Daniel J. Kass,
Shulin Qin,
Xiaohong Wang,
Michael M. Myerburg,
Barbara Methé,
Adam Fitch,
Jonathan K. Alder,
Panayiotis V. Benos,
Bryan J. McVerry,
Mauricio Rojas,
Alison Morris,
Georgios D Kitsios
Publication year - 2020
Publication title -
thorax
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.083
H-Index - 221
eISSN - 1468-3296
pISSN - 0040-6376
DOI - 10.1136/thoraxjnl-2020-214770
Subject(s) - medicine , idiopathic pulmonary fibrosis , lung , pathology , copd , lung transplantation , interstitial lung disease , microbiome , fibrosis , biology , bioinformatics
Lung microbiota profiles in patients with early idiopathic pulmonary fibrosis (IPF) have been associated with disease progression; however, the topographic heterogeneity of lung microbiota and their roles in advanced IPF are unknown.