Open AccessPUMA – pooled uranium miners analysis: cohort profile
Author(s) -
Estelle Rage,
David B. Richardson,
Paul A. Demers,
Minh Do,
Nora Fenske,
Michaela Kreuzer,
Jonathan M. Samet,
Charles L. Wiggins,
Mary K. SchubauerBerigan,
Kaitlin KellyReif,
Ladislav Tomášek,
Lydia B. Zablotska,
Dominique Laurier
Publication year - 2020
Publication title -
occupational and environmental medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.458
H-Index - 141
eISSN - 1470-7926
pISSN - 1351-0711
DOI - 10.1136/oemed-2019-105981
Subject(s) - radon , environmental health , medicine , lung cancer , epidemiology , cohort study , radon daughters , demography , pathology , physics , quantum mechanics , sociology
Epidemiological studies of underground miners have provided clear evidence that inhalation of radon decay products causes lung cancer. Moreover, these studies have served as a quantitative basis for estimation of radon-associated excess lung cancer risk. However, questions remain regarding the effects of exposure to the low levels of radon decay products typically encountered in contemporary occupational and environmental settings on the risk of lung cancer and other diseases, and on the modifiers of these associations. These issues are of central importance for estimation of risks associated with residential and occupational radon exposures.