Open AccessUltra-high resolution array painting facilitates breakpoint sequencing
Author(s) -
Susan Gribble,
Dimitrios Rafail Kalaitzopoulos,
D. C. Burford,
Elena Prigmore,
Rebecca R. Selzer,
Bee Ling Ng,
Nick S. W. Matthews,
Keith Porter,
Rebecca Curley,
Sarah Lindsay,
Júlia Baptista,
Todd Richmond,
Nigel P. Carter
Publication year - 2006
Publication title -
journal of medical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.439
H-Index - 170
eISSN - 1468-6244
pISSN - 0022-2593
DOI - 10.1136/jmg.2006.044909
Subject(s) - breakpoint , computational biology , biology , genetics , computer science , gene , chromosomal translocation
To describe a considerably advanced method of array painting, which allows the rapid, ultra-high resolution mapping of translocation breakpoints such that rearrangement junction fragments can be amplified directly and sequenced.