Skewed X chromosome inactivation and early-onset breast cancer | Zendy

Jeffery P. Struewing | Zendy; Marbin Pineda | Zendy; Mark E. Sherman | Zendy; Jolanta Lissowska | Zendy; L A Brinton | Zendy; Beata Pepłońska | Zendy; Alicja BardinMikolajczak | Zendy; Montserrat GarcíaClosas | Zendy

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Skewed X chromosome inactivation and early-onset breast cancer

Author(s) -

Jeffery P. Struewing,

Marbin Pineda,

Mark E. Sherman,

Jolanta Lissowska,

L A Brinton,

Beata Pepłońska,

Alicja BardinMikolajczak,

Montserrat GarcíaClosas

Publication year - 2005

Publication title -

journal of medical genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.439

H-Index - 170

eISSN - 1468-6244

pISSN - 0022-2593

DOI - 10.1136/jmg.2005.033134

Subject(s) - hpaii , breast cancer , population , x inactivation , biology , chromosome , skewed x inactivation , cancer , medicine , x chromosome , genetics , oncology , gene , dna methylation , gene expression , environmental health

Skewed X chromosome inactivation may be more common in women with epithelial ovarian cancer and early-onset breast cancer. We tested this hypothesis in a group of 235 breast cancer patients and 253 controls (mean age 45.8 years) from a larger population based case control study.

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