Open AccessOtitis media susceptibility and shifts in the head and neck microbiome due to SPINK5 variants
Author(s) -
Daniel N. Frank,
Arnaud P. J. Giese,
Lena Hafrén,
Tori C. Bootpetch,
Talitha Karisse Yarza,
Matthew J. Steritz,
Melquiadesa Pedro,
Patrick John Labra,
Kathleen A. Daly,
Ma. Leah C. Tantoco,
Wasyl Szeremeta,
Maria Rina T. ReyesQuintos,
Niaz Ahankoob,
Erasmo Gonzalo D.V. Llanes,
Harold S. Pine,
Sairah Yousaf,
Diana Ir,
Elisabet Einarsdóttir,
Rhodieleen Anne R. de la Cruz,
Nanette R. Lee,
Rachelle Marie A. ato,
Charles E. Robertson,
Kimberly Mae C. Ong,
Jose Pedrito M. Magno,
Alessandra Nadine E. Chiong,
Ma. Carmina Espiritu-Chiong,
Maria Luz San Agustin,
Teresa Luisa Cruz,
Generoso T. Abes,
Michael J. Bamshad,
Eva Maria Cutiongcode la Paz,
Juha Kere,
Deborah A. Nickerson,
Karen L. Mohlke,
Saima Riazuddin,
Abner L. Chan,
Petri S. Mattila,
Suzanne M. Leal,
Allen F. Ryan,
Zubair M. Ahmed,
Tasnee Chonmaitree,
Michèle M. Sale,
Charlotte M. Chiong,
Regie Lyn P. SantosCortez
Publication year - 2020
Publication title -
journal of medical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.439
H-Index - 170
eISSN - 1468-6244
pISSN - 0022-2593
DOI - 10.1136/jmedgenet-2020-106844
Subject(s) - middle ear , outer ear , biology , otitis , sanger sequencing , genetics , exome sequencing , exome , microbiome , dna sequencing , gene , anatomy , mutation
Otitis media (OM) susceptibility has significant heritability; however, the role of rare variants in OM is mostly unknown. Our goal is to identify novel rare variants that confer OM susceptibility.