Open AccessImpact of aging on the immune response to traumatic brain injury (AIm:TBI) study protocol
Author(s) -
Hilaire J. Thompson,
Frederick P. Rivara,
Kyra J. Becker,
Ronald V. Maier,
Nancy Temkin
Publication year - 2019
Publication title -
injury prevention
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.745
H-Index - 83
eISSN - 1475-5785
pISSN - 1353-8047
DOI - 10.1136/injuryprev-2019-043325
Subject(s) - traumatic brain injury , medicine , psychological intervention , young adult , logistic regression , injury prevention , poison control , quality of life (healthcare) , glasgow outcome scale , prospective cohort study , cohort study , falls in older adults , physical therapy , gerontology , psychiatry , emergency medicine , nursing
Traumatic brain injury (TBI) in older adults leads to considerable morbidity and mortality. Outcomes among older adults with TBI are disparately worse than in younger adults. Differences in immunological response to injury may account for at least some of this disparity. Understanding how ageing differentially affects the immune response to TBI and how older age and these immunological changes affect the natural history of recovery following TBI are the goals of this study.