Open AccessSequencing chemotherapy before radiotherapy for women with stage IIIC endometrial cancer
Author(s) -
Deepa Maheswari Narasimhulu,
Matthew S. Block,
Amy L. Weaver,
Michaela E. McGree,
Amanika Kumar,
Carrie Langstraat,
Ivy A. Petersen,
Andrea Mariani,
Gretchen Glaser
Publication year - 2021
Publication title -
international journal of gynecological cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.901
H-Index - 87
eISSN - 1525-1438
pISSN - 1048-891X
DOI - 10.1136/ijgc-2020-002158
Subject(s) - medicine , radiation therapy , chemotherapy , endometrial cancer , uterine cancer , oncology , stage (stratigraphy) , cancer , surgery , paleontology , biology
It is unclear how to best sequence adjuvant chemotherapy and radiotherapy for advanced endometrial cancer. We studied the outcomes for women treated with chemotherapy before radiotherapy in a chemotherapy-first (chemotherapy for 6 cycles followed radiotherapy) or 'sandwich' approach (chemotherapy for 3 cycles followed by radiotherapy and subsequently chemotherapy for 3 cycles).