Open AccessClinical and echocardiographic outcomes in heart failure associated with methamphetamine use and cessation
Author(s) -
Harpreet Bhatia,
Marin Nishimura,
Stephen Dickson,
Eric Adler,
Barry Greenberg,
Isac C. Thomas
Publication year - 2020
Publication title -
heart
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.184
H-Index - 183
eISSN - 1468-201X
pISSN - 1355-6037
DOI - 10.1136/heartjnl-2020-317635
Subject(s) - medicine , heart failure , ejection fraction , cardiology , methamphetamine , diastole , retrospective cohort study , blood pressure , smoking cessation , pathology
Methamphetamine use is associated with systolic dysfunction, pulmonary arterial hypertension and may also be associated with diastolic dysfunction. The impact of methamphetamine cessation on methamphetamine-associated heart failure (MethHF) remains poorly characterised. We aimed to longitudinally characterise methamphetamine-associated heart failure patients with reduced (METHrEF) and preserved (METHpEF) left ventricular ejection fraction (EF), and evaluate the relationship between methamphetamine cessation and clinical outcomes.