Open AccessAngiogenin maintains gut microbe homeostasis by balancing α-Proteobacteria and Lachnospiraceae
Author(s) -
Desen Sun,
Rongpan Bai,
Wei Zhou,
Zhengrong Yao,
Yaxin Liu,
Shu Tang,
Xiaolong Ge,
Lun Luo,
Chi Luo,
Guofu Hu,
Jinghao Sheng,
Zhengping Xu
Publication year - 2020
Publication title -
gut
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.413
H-Index - 293
eISSN - 1468-3288
pISSN - 0017-5749
DOI - 10.1136/gutjnl-2019-320135
Subject(s) - lachnospiraceae , dysbiosis , gut flora , microbiology and biotechnology , biology , colitis , proteobacteria , bacteroides , immunology , bacteria , firmicutes , genetics , 16s ribosomal rna
Antimicrobial peptides (AMPs) play essential roles in maintaining gut health and are associated with IBD. This study is to elucidate the effect of angiogenin (ANG), an intestine-secreted AMP, on gut microbiota and its relevance with IBD.