Open AccessInflammatory bowel disease in India: challenges and opportunities
Author(s) -
Alice Snell,
Jonathan Segal,
Jimmy K. Limdi,
Rupa Banerjee
Publication year - 2020
Publication title -
frontline gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.919
H-Index - 13
eISSN - 2041-4145
pISSN - 2041-4137
DOI - 10.1136/flgastro-2020-101500
Subject(s) - disease , medicine , inflammatory bowel disease , subject matter , epidemiology , clinical phenotype , etiology , developing country , intensive care medicine , economic growth , pathology , biology , biochemistry , economics , curriculum , gene , phenotype
Evidence is emerging that inflammatory bowel diseases (IBDs) are becoming increasingly prevalent in developing countries, altering the previously held view that these were diseases of the West. Within this is a substantial increase in the burden of this disease in India, a matter of great importance to the country itself as well as in furthering our understanding of the disease. There is comparatively less data on this, both from the epidemiological standpoint as well as on disease pathogenesis in this particular cohort and is very much a subject matter of evolving understanding and research. This article aims to look at the changing global distribution of the disease and its implications. The Indian disease phenotype, and the aetiology of disease development will also be addressed with particular focus on differing pathogenetic processes in the Indian subpopulation, with consideration of what clues may be offered by the increasing incidence of the disease in this developing nation. Available evidence will be evaluated with the objective of providing a comprehensive overview of the development of IBD in India.