Open AccessValidation of RP-HPLC method to assess the compatibility of metoclopramide and midazolam intravenous mixture used in patients with cancer
Author(s) -
Seydou Sanogo,
Paolo Silimbani,
Raffaella Gaggeri,
Romina Rossi,
Lisa Elviri,
Marco Maltoni,
Carla Masini
Publication year - 2018
Publication title -
european journal of hospital pharmacy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.313
H-Index - 14
eISSN - 2047-9964
pISSN - 2047-9956
DOI - 10.1136/ejhpharm-2018-001544
Subject(s) - compatibility (geochemistry) , high performance liquid chromatography , metoclopramide , chromatography , midazolam , clinical practice , chemistry , medicine , anesthesia , materials science , nursing , sedation , composite material , vomiting
The delivery of intravenous medication by continuous infusion is necessary and widespread for treatment of patients with advanced cancer. Few scientific papers have focused on assessment of the chemical compatibility of these therapeutic mixtures. An analytical assessment of the physical and chemical compatibility of these combinations is needed.